Phase Precession Through Synaptic Facilitation

Phase Precession Through Synaptic Facilitation

Phase precession is a relational code that is thought to be important for episodic-like memory, for instance, the learning of a sequence of places. In the hippocampus, places are encoded through bursting activity of so-called place cells. The spikes in such a burst exhibit a precession of their firing phases relative to field potential theta oscillations (4-12 Hz); the theta phase of action pot...

Learned Hippocampal Sequential Coding through Phase Precession

The hippocampal formation is necessary for spatial learning and memory in rats. One aspect of this cognitive function, the ability to remember path sequences, is thought to be achieved through phase precession. The two components of phase precession are a strong theta rhythm (8-12 Hz) in the local field potential and place-selective neurons, which fire selectively while the rat is in a particul...

New and corrected simulations of synaptic facilitation.

Tang et al. (2000) demonstrated that, at the crayfish neuromuscular junction, both the accumulation and the decay properties of short-term synaptic facilitation (STF) are strongly affected by the addition of a fast high-affinity Ca buffer, suggesting a role of residual free Ca in the induction of STF. The authors proposed that the experimental results can be explained by a secretion model with ...

Phonological Facilitation Through Translation

Single-trial phase precession in the hippocampus.

During the crossing of the place field of a pyramidal cell in the rat hippocampus, the firing phase of the cell decreases with respect to the local theta rhythm. This phase precession is usually studied on the basis of data in which many place field traversals are pooled together. Here we study properties of phase precession in single trials. We found that single-trial and pooled-trial phase pr...